Corneal Surgeries

Corneal surgeries are specialized ophthalmic procedures that provide treatment to repair, reshape, or replace the cornea (visualized as the clear outermost layer of the eye). These procedures are of utmost importance in restoring vision upon the attack of corneal diseases, injuries, or degeneration.

These special eye surgeries can improve visual clarity and quality of life dramatically in correcting 

refractive errors, or treating keratoconus or corneal scars.

Why Choose Khetarpal Hospital for Keratoplasty surgeries?

  • Corneal Specialists with Extensive Experience
  • Association with Licensed Eye Banks for safe donor tissue
  • Micro-Incision, Sutureless Techniques available in select cases
  • Post-Operative Vision Rehabilitation and long-term care
  • High Success Rates and infection control protocols

     

Other Age-Related Eye Treatments

  • Diabetic Retinopathy
  • Macular Degeneration 
  • Glaucoma 
  • Cataract Surgeries
  •  Refractive Lens Exchange (RLE)

What Is Keratoplasty?

Corneal transplant, also known as keratoplasty, is a surgical procedure to replace a damaged or diseased cornea with healthy donor tissue. The cornea is the transparent, dome-shaped surface that helps focus light into the eye. When it becomes cloudy, scarred, or misshapen, vision can be severely

Types of Corneal Transplant Procedures

There are several types of keratoplasty, and the choice depends on the extent and location of corneal damage:

A full-thickness transplant where the entire corneal layer is replaced. Ideal for extensive damage affecting all corneal layers.

Only the front layers of the cornea are replaced, preserving the healthy inner endothelium. Suitable for conditions like keratoconus or surface scars.

 Replaces the back portion of the cornea, including the endothelium and Descemet’s membrane. Used for diseases like Fuchs’ dystrophy.

A more refined version of DSAEK, replacing only the Descemet’s membrane and endothelium. Offers faster recovery and better visual outcomes.

You may be a good candidate if you have:

  • Keratoconus or corneal thinning unresponsive to lenses or cross-linking
  • Fuchs’ endothelial dystrophy or other endothelial dysfunction
  • Corneal scarring from injury, infection, or surgery
  • Corneal edema or swelling that leads to pain or blurry vision
  • Corneal opacities or degeneration
  • Failure of a previous transplant

A complete eye exam, including corneal thickness and endothelial cell count, helps determine the best approach.

  • Restores Clear Vision – Especially when other treatments are no longer effective
  • Customized Options – Lamellar techniques preserve healthy tissue and reduce rejection risk
  • Improved Quality of Life – Enables daily activities like reading, driving, and working
  • Proven Success – Decades of data support the safety and efficacy of corneal transplantation
  • Minimal Discomfort – Modern surgical methods are precise, safe, and outpatient-based

Ideal Candidates for Corneal Transplant

You may be a good candidate if you have:

  • Keratoconus or corneal thinning unresponsive to lenses or cross-linking
  • Fuchs’ endothelial dystrophy or other endothelial dysfunction
  • Corneal scarring from injury, infection, or surgery
  • Corneal edema or swelling that leads to pain or blurry vision
  • Corneal opacities or degeneration
  • Failure of a previous transplant

A complete eye exam, including corneal thickness and endothelial cell count, helps determine the best approach.

Benefits of Corneal Transplant

  • Restores Clear Vision – Especially when other treatments are no longer effective
  • Customized Options – Lamellar techniques preserve healthy tissue and reduce rejection risk
  • Improved Quality of Life – Enables daily activities like reading, driving, and working
  • Proven Success – Decades of data support the safety and efficacy of corneal transplantation
  • Minimal Discomfort – Modern surgical methods are precise, safe, and outpatient-based

 

Corneal transplant surgery can be life-changing, bringing back vision that was once thought lost. If you’re struggling with corneal disease or severe vision loss. 

FAQs About Corneal Transplant (Keratoplasty)

Recovery time varies by procedure. Full-thickness transplants (PK) may take several months to a year for optimal vision, while lamellar procedures like DMEK or DSAEK often have faster healing within a few weeks.

Rejection is possible, but less common than with other organ transplants. The risk is significantly minimized with proper follow-up and use of prescribed steroid eye drops.

Possibly, yes. While vision improves substantially, you may need glasses or contact lenses for best clarity, especially after full-thickness transplants.

Descemet Membrane Endothelial Keratoplasty (DMEK) and Descemet Stripping Endothelial Keratoplasty (DSEK) are advanced, minimally invasive corneal transplant techniques used to treat diseases of the cornea’s innermost layer—the endothelium. These procedures selectively replace only the damaged endothelial layer, resulting in faster recovery, fewer complications, and excellent visual outcomes.

What Is the DMEK/DSEK Procedure?

Both DMEK and DSEK fall under the category of lamellar keratoplasty, meaning only a portion of the cornea is transplanted:

DMEK (Descemet Membrane Endothelial Keratoplasty)
Replaces only the Descemet’s membrane and endothelium—a thin, delicate layer of tissue. It offers the most natural anatomical restoration with the clearest possible vision.

DSEK (Descemet Stripping Endothelial Keratoplasty)
Transplants the Descemet’s membrane, endothelium, and a thin layer of donor stroma. Slightly thicker than DMEK, but easier to handle during surgery and still delivers excellent outcomes.

How the Procedure Works

Diagnosis & Evaluation

A full eye exam and corneal imaging confirm endothelial dysfunction, commonly due to Fuchs’ dystrophy, pseudophakic bullous keratopathy, or previous graft failure.

Surgical Technique

Post-Operative Care

Key Benefits of DMEK/DSEK

  • Faster Visual Recovery – Most patients see significant improvements within weeks (especially with DMEK).
  • Minimal Rejection Risk – DMEK has the lowest rejection rate of any corneal transplant technique (<1%).
  •  High-Quality Vision – DMEK restores nearly natural corneal anatomy for clearer, sharper vision.
  • Minimally Invasive – Small incision, no sutures required, and reduced risk of complications.
  • Better Long-Term Outcomes – Strong, stable grafts with fewer long-term side effects compared to full-thickness transplants.

FAQs About DMEK/DSEK

Both are highly effective, but DMEK provides superior visual clarity and a lower rejection rate. However, DSEK may be preferred in complex cases where handling extremely thin tissue is challenging.

No. The procedure is performed under local or topical anesthesia, and most patients experience minimal discomfort. Recovery is generally smooth with proper care.

DMEK/DSEK grafts can last many years, often a decade or more. Regular follow-ups and adherence to post-op care increase long-term success.

What is Phototherapeutic keratectomy (PTK) ?

Phototherapeutic keratectomy is a laser surgical procedure indicated for anterior corneal surface opacities and irregularities with the aim of visual restoration and pain relief; it employs an excimer laser for accurate reshaping or smoothing of the cornea.

Benefits of PTK

  • Restores Vision Clarity: The procedure successfully removes corneal scars, opacities, or dystrophies, thus restoring clarity of vision.
  • Reduces Eye Discomfort: The procedure alleviates recurrent corneal erosions and painful irregularities on the surface.
  • Minimally Invasive: No incisions are required; laser treatment is highly controlled.
  • Customizable Treatment: The laser is capable of focusing on specific problem areas while not injuring any healthy tissues.
  • Quick Recovery Time: Most patients will notice improvement from weeks to days.

Who Are the Ideal Candidates for PTK?

You would be a good candidate for PTK if you:

  • Have corneal surface irregularities such as scars, dystrophies, and opacities.
  • Have recurrent corneal erosions that do not respond to nonsurgical treatment.
  • Do not qualify for a corneal transplant or would rather delay an invasive intervention.
  • Have reasonable expectations and good overall eye health (excluding the surface condition).

Always speak with your ophthalmologist. They will work to affirm your eligibility through corneal imaging and clinical evaluation. 

Frequently Asked Questions

No. PTK treats medical corneal conditions, while LASIK primarily treats vision correction  like myopia, hyperopia, or astigmatism).

The procedure is usually painless; anesthetic drops are used, and mild discomfort may occur during recovery.

Healing begins within the first few days, but total improvement of vision can take weeks depending on the condition being treated.

What is Corneal Cross Linkage (CXL)

Corneal Cross Linkage (CXL) is a treatment that is provided at minimal cost to the patient and is non-surgically. This treatment is carried out on the cornea with the help of vitamin B2 (riboflavin) drops beamed inside through ultraviolet light. The main indication of this procedure is the interruption of keratoconus disease and other corneal ectasias. 

The Benefits of CXS

  • Stops Thinning of Cornea: prevents keratoconus and other corneal diseases.
  • Strengthens Corneal Structure: Increases biomechanical stability of the cornea through new collagen bonds.
  • Need for transplant reduced: It helps avoid or postpone corneal transplantation in many patients.
  • Vision improves: The cornea may flatten over time, and vision improves.
  • Safe: Effective with high success rates.

Ideal candidate for CXL.

You might be a good candidate if you:

  • Have keratoconus, pellucid marginal degeneration, or post-LASIK ectasia.
  • Progressively show signs of corneal thinning or steepening.
  • Typically between 12 and 40 years, when progression most likely to happen.
  • Corneal thickness should be around ~400 microns, but this is protocol specific.
  • Do not have active infections or scarring of corneal tissue with a history of autoimmune disorders.

The ophthalmologist will determine eligibility through corneal topography and request for a test.

Frequently Asked Questions

The primary purpose of CXL is to halt disease progression rather than reverse keratoconus. Many patients report stabilized vision or a gradual or slight improvement over time.

Most suffer mild discomfort, burning, or sensitivity for a few days. Healing is easier with the epithelium-on (transepithelial) technique, though healing is more predictable with epithelium-off.

The results are expected to last for a long time; most patients receive only one treatment during their lifetime to achieve stabilization.